Tooth Stem Cell, Tooth Cell Banking in Bangkok Thailand

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Tooth Stem Cell

MSC for Therapy

Mesenchymal stem cells show more promise for therapeutic application than any other stem cell except for ES.

There are several therapeutic applications for MSC in late stage clinical trials and many more under development.

Mesenchymal Stem Cell Treatment for Cerebral Palsy

MSC’s quickly and significantly improves recovery of motor function, within two weeks, in an animal model for the ischemic brain injury that occurs in about 10 percent of babies with cerebral palsy.

Studies performed at the Medical College of Georgia.

First presented at the 34th annual meeting of the Child Neurology Society Sept. 28-Oct. 1, 2005 in Los Angeles

Cerebral Palsy Mouse

Mesenchymal Stem Cells to treat Liver Disease

Mesenchymal Stem Cells have been found capable of regenerating liver cells in mouse model.

Fetal and adult liver stem cells for liver regeneration and tissue engineering. Fiegel HC, Lange C, Kneser U, Lambrecht W, Zander AR, Rogiers X, Kluth D. J Cell Mol Med. 2006 Jul-Sep;10(3):577-87.

Mesenchymal Stem Cells treat Diabetes

Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells.

Timper K, Seboek D, Eberhardt M, Linscheid P, Christ-Crain M, Keller U, Müller B, Zulewski H. Department of Research, University Hospital, Basel, Switzerland. Biochem Biophys Res Commun. 2006 Mar 24;341(4):1135-40. PMID: 16460677

Findings : Mesenchymal stem cells (MSC) from mouse bone marrow were shown to adopt a pancreatic endocrine phenotype in vitro and to reverse diabetes in an animal model.

Insulin was the first protein to have its primary structure determined
Chang, X., et al. Biochemistry v36 pp.9409-9422 , 1997

Mesenchymal Stem Cells treat stroke

Autologous mesenchymal stem cell transplantation in stroke patients.

Bang OY, Lee JS, Lee PH, Lee G. Ann Neurol. 2005 Jun;57(6):874-82. PMID: 15929052. Department of Neurology, School of Medicine, Ajou University, Suwon, South Korea.

Findings : Mesenchymal stem cell (MSC) transplantation improves recovery from ischemic stroke in humans stroke patients.

Image by Mike de la Flor

Clinical Trials Mesenchymal Stem Cells

Autologous mesenchymal stem cell transplantation in stroke patients.

Clinical Trial for ID Number

Graft Verses Host Disease NCT00504803

Crohn’s Disease NCT00294112

Multiple Sclerosis NCT00395200

Type 1 Diabetes Mellitus NCT00646724

End-stage Liver Disease NCT00420134

Systemic Lupus Erythematosus NCT00698191

Wound Healing; Burn NCT00609661

Adult Periodontitis NCT00221130

Distal Tibial Fractures NCT00512434

59 clinical trials being monitored by FDA www.clinicaltrials.gov

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